منابع مشابه
Surface Phagocytosis
Experiments recently reported (18) have been interpreted to indicate that surface phagocytosis plays no significant part in natural antipneumococcal defense. A repetition of these experiments has revealed: (a) that the cellular content of the leucocytic suspensions used in the phagocytic tests was of a different order of magnitude from that of the exudates which usually exist in infected tissue...
متن کاملChanges in neutrophil surface protein composition accompany phagocytosis.
Phagocytosis is a critical host defense mechanism of neutrophils. In this study, membrane protein changes occurring during phagocytosis were studied in human neutrophils using surface radiolabeling before or after phagocytosis of various target particles. Cells were labeled at the cell surface using lactoperoxidase-catalyzed iodination or neuraminidase-galactose oxidase-NaB3H4, galactose oxidas...
متن کاملPhagocytosis and surface morphology in cultured retinal pigment epithelial cells.
Phagocytosis of latex spheres was studied in explant cultures of retinal pigment epithelium from rabbit, calf, and rat (normal and dystrophic). Calf and rabbit pigment epithelial cells showed a "latent period" of about 12 and 17 hr, respectively, during which latex spheres were not ingested even when the cultures were pre-incubated for up to 24 hr prior to exposure. Scanning electron microscopy...
متن کاملThe Effect of Surface-active Agents on Phagocytosis.
According to the theoretical formulation of Fenn (1921), based in part on the previous work of Tait (1918) and Rhumbler (1914), a decrease in free surface energy occurs when a particle is ingested by a phagocyte. Mudd and Mudd (1933) offered experimental evidence in support of this concept in their elucidation of the role played by opsonins (and nonimmune serum) in promoting phagocytosis. Bacte...
متن کاملSurface tension influences cell shape and phagocytosis in alveolar macrophages.
The effect of surface tension on alveolar macrophage shape and phagocytosis was assessed in vivo and in vitro. Surface tension was regulated in vivo by conditionally expressing surfactant protein (SP)-B in Sftpb-/- mice. Increased surface tension and respiratory distress were produced by depletion of SP-B and were readily reversed by repletion of SP-B in vivo. Electron microscopy was used to de...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1958
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.107.1.1